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Open Orphan #ORPH – hVIVO to present at 2020 ERS International Congress
Open Orphan plc (ORPH), a rapidly growing specialist CRO pharmaceutical services company which is the world leader in the testing of vaccines and antivirals using human challenge clinical trials is pleased to announce that its subsidiary, hVIVO, will be presenting at the European Respiratory Society Congress being held on 7th – 9th September, 2020.
The presentation will discuss the safety and pathogenicity results of a new RSV infection model in older adults aged 60-75-year-old. This model enables the exploration of RSV vaccine-induced immune responses and efficacy in the context of potential immune senescence. It also enables the potential Identification of correlates of protection from RSV infection and disease in one of the vaccine’s target populations.
Alex J Mann, Director, Clinical Science, commented; “We are delighted to have been accepted to present at the prestigious ERS International Congress and share our findings. The data summarised in the presentation and ePoster highlights the model’s safety, disease characteristics, and suitability for the further assessment of vaccines and drugs targeted at the 60-75-year-old population, as well as its potential to continue that progression.”
Oral presentation details:
Title : Late Breaking Abstract -Experimental Respiratory Syncytial Virus Infection in Adults 60-75 years
Authors : Alex J Mann, Maria Kalinova, Andrew Catchpole, Olesya Rusyn, Veronika Horvathova, Kingsley Eze, Marco De Sa, Alan S Bell
Date & Time : 9th September 2020 at 9:30am – 10.30am
Session Category : Airway infection: the microbiome and beyond
Presenter: Alex J Mann, Director of Clinical Sciences
Location : Online
Conference Reference Number : Channel 4
A copy of the presentation materials and the poster can be found here: https://hvivo.com/news-media/scientific-papers/
For further information please contact
| Open Orphan plc | +353 (0)1 644 0007 |
| Cathal Friel, Executive Chairman | |
| Arden Partners plc (Nominated Adviser and Joint Broker) | +44 (0)20 7614 5900 |
| John Llewellyn-Lloyd / Benjamin Cryer / Dan Gee-Summons | |
| finnCap plc (Joint Broker) | +44 (0) 20 7220 500 |
| Geoff Nash / James Thompson/ Richard Chambers | |
| Davy (Euronext Growth Adviser and Joint Broker) | +353 (0)1 679 6363 |
| Anthony Farrell | |
| Camarco (Financial PR) | +44 (0)20 3757 4980 |
| Tom Huddart / Hugo Liddy |
Notes to Editors – Open Orphan:
Open Orphan is a rapidly growing niche CRO pharmaceutical services company which is a world leader in the testing of vaccines and antivirals through the use of human challenge clinical trials. Conducted from Europe’s only 24-bedroom quarantine clinic with onsite virology providing individually isolated rooms and connected to our specialist laboratory facility. hVIVO’s challenge studies require healthy volunteers to take part, volunteers are recruited through FluCamp, learn more at www.FluCamp.com . The hVIVO facility offers highly specialised virology and immunology laboratory services to support pre-clinical and clinical respiratory drug, antiviral, and vaccine discovery and development. Reliable laboratory analysis underpinned by scientific expertise is essential when processing and analysing clinical samples. Robust quality processes support our team of scientists in the delivery of submission ready data.
The Company has a leading portfolio of 8 viral challenge study models which are: 2 FLU, 2 RSV, 1 HRV, 1 Asthma, 1 cough and 1 COPD viral challenge models. As announced in early March, Open Orphan is rapidly advancing a number of Coronavirus challenge study models and expects to be helping many COVID-19 vaccine development companies to test their vaccines. No other company in the world has such a portfolio, with only two competitors globally having 1 challenge study model each. hVIVO also works with companies in the UK and Ireland to provide COVID-19 testing to staff to protect staff and customers from a workplace COVID-19 outbreak through its COVID Clear offering.
Open Orphan comprises of two commercial specialist CRO services businesses, hVIVO and Venn Life Sciences and is also developing an early stage orphan drug genomics data platform business. This platform captures valuable genetic data from patient populations with specific diseases with designated orphan drug status and incorporating AI tools. In June 2019, Open Orphan acquired AIM-listed Venn Life Sciences Holdings plc in a reverse take-over and in January 2020 it completed the merger with hVIVO plc in January 2020. Venn is an integrated drug development consultancy firm which offers CMC (chemistry, manufacturing and controls), preclinical, Phase I & II clinical trials design and execution. The merger with hVIVO created a European full pharma services company broadening the Company’s customer base and with complementary specialist CRO services, widened the range of the Company’s service offerings.
Cathal Friel, Open Orphan #ORPH CEO confirms to Proactive Investors that the hVIVO deal is done
Cathal Friel, CEO of Open Orphan announces that the hVIVO deal is finally in the bag and tells Proactive London what the timeline for shareholders now looks like. Cathal also provides some news on the Genomic Database and explains how he expects hVIVO to make a profit.
Open Orphan plc (ORPH) Investor Event Attendance and Presentation
Open Orphan, a European-focussed, rare and orphan drug consulting services platform, is pleased to announce that the Company will be attending and presenting at The London Investor Show at Novotel London West, London, W6 8DR this Friday 25th October 2019.
Maurice Treacy, Open Orphan’s Chief Commercial Officer, will be in attendance and will be presenting in Conference Room 1 from 11:50am – 12:20pm. Afterwards there will be an opportunity for existing and potential shareholders to discuss the Company’s business plans moving forward.
The event will run from 09:30am – 5:00pm and all parties interested in attending can obtain a free ticket by using the promotional code OPENORPHAN19 when ordering a ticket from the following link: http://www.eventdata.co.uk/Forms/Form.aspx?FormRef=LISA9Visitor .
Enquiries:
Open Orphan Plc Tel: +353 (0)1 6440007
Cathal Friel, Chief Executive Officer
Arden Partners (Nominated Adviser and Joint Broker) Tel: +44 (0)20 7614 5900
John Llewellyn-Lloyd / Ruari McGirr / Benjamin Cryer
Davy (Euronext Growth Adviser and Joint Broker) Tel: +353 (0)1 679 6363
Anthony Farrell (Corporate Finance)
Camarco (Financial PR) Tel: +44 (0)20 3757 4980
Tom Huddart / Billy Clegg / Daniel Sherwen
Notes to Editors:
Open Orphan plc is a European-focused, rare and orphan drug consulting services platform. The Company intends to roll up a number of orphan drug services business. Open Orphan has two data driven digital platforms, a Genomic Health Data Platform, which is establishing a rare disease database and a Virtual Rep platform enabling pharmaceutical companies to engage key opinion leaders and physicians. The Company is targeting rapid growth in one of the fastest growing sectors in the global pharmaceutical industry targeting under-supplied treatment for life threatening or very serious diseases and rare disorders.
Open Orphan #ORPH signs strategic collaboration agreement with Empiric Logic
Open Orphan, a European-focussed, rare and orphan drug consulting services platform, is pleased to announce it has signed a new strategic collaboration agreement (“the Collaboration”) with Empiric Logic to build on the earlier work performed by Open Orphan and complete the build out of Open Orphan’s Health Data platform, Europe’s first rare disease, advocacy-led genomic database.
Empiric Logic, a leading managed software service company which provides software to the Life Sciences, Pharma, Pharma Services and Biotech sectors, will incorporate its propriety, privacy preserving, and artificial intelligence enabled software into Open Orphan’s Health Data platform to aid the collection and management capabilities of the software.
The Collaboration is the final stage in the completion of Open Orphan’s Genomic Health Data platform and will speed up its launch. The platform builds on the genomic analysis, database architecture know-how and prior professional experience between the founders of Empiric Logic and Maurice Treacy, Chief Commercial Officer at Open Orphan.
Cathal Friel, Chief Executive of Open Orphan commented:
“This is an exciting step towards the completion of our genomic Health Data platform, and we are delighted to have Empiric on board to help us quickly and securely become one of the largest databases of rare disease patients in Europe.”
Gareth O’Sullivan, CEO at Empiric Logic commented:
“Empiric Logic is delighted to be supporting the Open Orphan team with the final steps of preparing the Genomic Health Data platform to accept first data.
As part of the rollout of the Open Orphan database, it will be making substantial use of our artificial intelligence capabilities, such as for identification of rare-disease genetic mutations, but also for the potential identification of patients for clinical trials going forward.”
Enquiries:
Open Orphan plc Tel: +353 1 644 0007
Cathal Friel, Chief Executive Officer
Arden Partners (Nominated Adviser and Joint Broker) Tel: +44 (0)20 7614 5900
John Llewellyn-Lloyd / Ruari McGirr / Benjamin Cryer
Davy (Euronext Growth Adviser and Joint Broker) Tel: +353 (0)1 679 6363
Anthony Farrell (Corporate Finance)
Camarco (Financial PR) Tel: +44 (0)20 3757 4980
Tom Huddart / Billy Clegg / Dan Sherwen
Notes to Editors on Open Orphan:
Open Orphan plc is a European-focused, rare and orphan drug consulting services platform. The Company intends to roll up a number of orphan drug services business. Open Orphan has two data driven digital platforms, a Genomic Health Data Platform, which is establishing a rare disease database and a Virtual Rep platform enabling pharmaceutical companies to engage key opinion leaders and physicians. The Company is targeting rapid growth in one of the fastest growing sectors in the global pharmaceutical industry targeting under-supplied treatment for life threatening or very serious diseases and rare disorders.
Notes to Editors on Empiric Logic:
Empiric Logic is a platform provider for health and genomics data analysis. This platform uses proprietary analysis software to automate key aspects of the collation, correlation and analysis of complex health and genomics data.