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#POLB Poolbeg Pharma PLC – POLB 001 LPS Trial Data to be Presented at IUIS
16 November 2023 – Poolbeg Pharma (AIM: POLB, OTCQB: POLBF, ‘Poolbeg’ or the ‘Company’), a biopharmaceutical company focussed on the development and commercialisation of innovative medicines targeting diseases with a high unmet medical need, announces that an abstract highlighting the potential of POLB 001 as a groundbreaking therapy has been accepted for presentation at the 18th International Congress of Immunology (‘IUIS’), to be held 27 November – 2 December 2023 in Cape Town, South Africa.
IUIS is the world’s leading conference in the field of immunology and attracts immunologists from universities, healthcare providers, independent research organisations and industry leaders. It serves as a premier platform for the exchange of the latest cutting-edge discoveries and advancements in immunological research.
The poster presentation will discuss POLB 001’s positive LPS human challenge trial results. POLB 001 is a potential treatment of severe influenza and Cytokine Release Syndrome (CRS) associated with cancer immunotherapies. CRS is a severe inflammatory response, which may be encountered as a side effect of some therapies, manifesting a range of symptoms that can rapidly progress to a severe life-threatening reaction. An effective therapy for CRS could unlock the benefits of cancer immunotherapies, benefiting patients and healthcare systems alike.
Title: Inhibition of local and systemic inflammatory responses by POLB 001, a novel p38 MAPK inhibitor, following in vivo LPS administration in healthy volunteers
Session Date: 1 December 2023
Presentation Time: 12pm – 1pm SAST
Location: Hall 2
Presenter: Digna de Bruin, The Centre for Human Drug Research
If you would like to meet with Poolbeg Pharma, get in touch at partnering@poolbegpharma.com
Jeremy Skillington, PhD, Chief Executive Officer of Poolbeg Pharma, said: “The acceptance of this abstract at the upcoming IUIS conference underscores the potential of POLB 001 as a groundbreaking therapy. Severe influenza and Cytokine Release Syndrome associated with cancer immunotherapies are significant problems and an effective drug that can address these issues would have a significant impact on global health.”
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Enquiries
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Poolbeg Pharma Plc Jeremy Skillington, CEO Ian O’Connell, CFO
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+44 (0) 207 183 1499 |
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Cavendish Capital Markets Ltd (Nominated Adviser & Joint Broker) Geoff Nash, Charlie Beeson, Nigel Birks, Harriet Ward (ECM)
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+44 (0) 207 220 0500 |
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Singer Capital Markets (Joint Broker) Phil Davies, Sam Butcher
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+44 (0) 207 496 3000 |
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J&E Davy (Joint Broker) Anthony Farrell, Niall Gilchrist
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+353 (0) 1 679 6363 |
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Optimum Strategic Communications Nick Bastin, Hana Malik, Vici Rabbetts
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+44 (0) 208 078 4357 |
About Poolbeg Pharma
Poolbeg Pharma plc is focussed on the development and commercialisation of innovative medicines targeting diseases with a high unmet medical need. Its model focusses upon developing its exciting clinical assets and commercialising approved and marketed drugs to fund the development of its robust pipeline of innovative products, thereby driving significant value creation.
Poolbeg is led by an experienced leadership team with a history of delivering significant shareholder value. The team and Board have been augmented with strong commercialisation expertise following the appointment of three former members of the Amryt Pharma plc leadership team, with the intention of repeating Amryt’s success and generating near term revenues.
Poolbeg’s clinical programmes target large addressable markets across cancer immunotherapies, infectious disease, and oral GLP-1 agonists for obesity and other metabolic conditions. It uses a cost-effective development philosophy to generate high quality human data to support partnering and further development. Its AI-led infectious disease programmes analyse unique data from human challenge trials to identify clinically relevant drug targets and treatments, leading to faster development and greater commercial appeal.
For more information, please go to www.poolbegpharma.com or follow us on Twitter and LinkedIn @PoolbegPharma.
#TEK TekCapital PLC – Launch of Lucyd Lyte 2.0 Smart Eyewear
Tekcapital Plc (AIM: TEK, OTCQB: TEKCF), the UK intellectual property investment group notes that Innovative Eyewear, Inc. (“Innovative Eyewear”) (NASDAQ: LUCY; LUCYW), the developer and retailer of smart eyewear under the Lucyd®, Nautica® and Eddie Bauer® brands, has announced the launch of Lucyd Lyte 2.0, (“Lyte 2.0”) a major upgrade to its flagship Lucyd Lyte audio eyewear platform.
The new Lucyd Lyte 2.0 line brings several advances to the company’s core product and is available now, in any optical prescription, at Lucyd.co. The Company intends to introduce the product to optical and specialty retail chains worldwide. The Lyte 2.0 marks the culmination of years of R&D to realize the company’s mission to make smart eyewear more accessible, useful and stylish for the optical and sunglass markets. New features of the Lyte 2.0 are as follows below:
· A four-speaker array provides immersive open-ear audio, that matches the sound quality of traditional earbuds without obstructing your hearing. The new speaker system provides an enhanced mid-range and bass response compared to the previous Lucyd Lyte.
· Audio input is improved with the introduction of dual noise-cancelling microphones. The Lyte 2.0 is ideal for recording audio content such as podcasts and voice messages and improves the fidelity of phone calls and input for voice assistants like Siri® compared to most built-in smartphone microphones.
· The battery life of the glasses has been improved to 12 hours of music playback and call time per charge, a 50% uplift over the previous model.
· The collection boasts 15 trending eyewear styles crafted by an experienced eyewear design team. 10 styles are available now, with the remaining five in pre-order until their expected availability in March 2023.
· The collection includes optical frames designed specifically for women and petite heads, as part of the company’s initiative to develop smart eyewear for all head shapes and sizes.
· The power and pairing indicator LEDs have been moved to a more discreet location in the inner temple.
· Touch controls now give an audible signal whenever the user adjusts volume or uses the other button functions, such as activating the voice assistant.
· Two new custom hinge types to enable a stronger, more aesthetically pleasing connection from the frontplate to the smart temple.
· Strength of the magnetic charging connection is improved, and the new collection is backwards compatible with the existing Lucyd Dock charger introduced with the original Lyte.
· The glasses use Bluetooth 5.2, providing improved connection stability over the previous 5.1 model.
· The glasses are offered with a new selection of over 20 custom lenses on Lucyd.co, now including gradient sunglasses and the latest cutting-edge Transitions® XTRActive Polarized and Signature Colors lenses.
· All of these features are added whilst maintaining price parity with traditional eyeglasses.
“Simply put, we believe there is no smart eyewear on the market that is as bold, beautiful and functional as the Lucyd Lyte 2.0,” says Harrison Gross, CEO of Innovative Eyewear. “We are in a unique place in history, where time-tested devices like the wristwatch and eyeglasses are being reimagined as onramps into our digital lives. I am grateful and amazed that my team was able to develop smart eyewear that truly delivers on the promise of wearables to make many forms of data and mobile computing easier to access, more natural and seamless. Unlike many companies that produce smart eyewear alongside dozens or hundreds of other products, we are singularly focused on this emerging category to make it useful and exciting for the consumer. I encourage everyone to upgrade their eyewear® with the Lyte 2.0, to see and hear the difference that years of thoughtful and rigorous development on a single core concept can make.”
Watch a video of the new glasses here.
About Innovative Eyewear, Inc.
Innovative Eyewear is a developer and retailer of cutting-edge smart eyewear, under the Lucyd®, Nautica® & Eddie Bauer® brands. True to our mission to Upgrade Your Eyewear®, our Bluetooth audio glasses allow users to stay safely and ergonomically connected to their digital lives, and are offered in hundreds of frame and lens combinations to meet the needs of the optical market. To learn more and explore our continuously evolving collection of smart eyewear, please visit www.lucyd.co.
Tekcapital currently owns 5,189,086 shares (approximately 71%) of Innovative Eyewear, Inc.
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Photos and images courtesy of Innovative Eyewear Inc.
For further information, please contact:
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Tekcapital Plc |
Via Flagstaff |
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Clifford M. Gross, Ph.D. |
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SP Angel Corporate Finance LLP (Nominated Adviser and Broker) |
+44 (0) 20 3470 0470 |
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Richard Morrison/Charlie Bouverat (Corporate Finance)/Abigail Wayne / Rob Rees (Corporate Broking)
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Flagstaff Strategic and Investor Communications |
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+44 (0) 20 7129 1474 |
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Tim Thompson/Andrea Seymour/Fergus Mellon |
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About Tekcapital plc
Tekcapital creates value from investing in new, university-developed discoveries that can enhance people’s lives and provides a range of technology transfer services to help organisations evaluate and commercialise new technologies. Tekcapital is quoted on the AIM market of the London Stock Exchange (AIM: symbol TEK) and is headquartered in the UK. For more information, please visit www.tekcapital.com.
LEI: 213800GOJTOV19FIFZ85
Forward-Looking Statements
This press release is for informational purposes only. The information herein does not constitute investment advice nor an offer to invest and may contain statements related to our future business and financial performance and future events or developments involving Innovative Eyewear, Inc., Lucyd or Tekcapital that may constitute forward-looking statements. These statements may be identified by words such as “expect,” “look forward to,” “anticipate” “intend,” “plan,” “believe,” “seek,” “estimate,” “will,” “project” or words of similar meaning. We may also make forward-looking statements in other reports, in presentations, in material delivered to customers, stakeholders and in press releases. In addition, our representatives may from time to time make oral forward-looking statements. Such statements may be based on the current expectations and certain assumptions of Tekcapital, Innovative Eyewear Inc. or Lucyd’s management. Please note that these are subject to a number of risks, uncertainties and factors, including, but not limited to those described in various disclosures. Should one or more of these risks or uncertainties materialize, or should underlying expectations not occur or assumptions prove incorrect, actual results, performance or achievements of Innovative Eyewear Inc., Lucyd and/or Tekcapital may vary materially from those described explicitly or implicitly in the relevant forward-looking statement. Other than as required by relevant regulation or law, neither Innovative Eyewear Inc, Lucyd nor Tekcapital intends, nor assumes any obligation, to update or revise these forward-looking statements in light of developments which differ from those anticipated.
#TEK Tek Capital PLC – Innovative Eyewear New Features for Vyrb App
Tekcapital Plc (AIM: TEK, OTCQB: TEKCF), the UK intellectual property investment group notes that Innovative Eyewear, Inc. (“Innovative Eyewear”) (NASDAQ: LUCY; LUCYW), the developer and retailer of smart eyewear under the Lucyd®, Nautica® and Eddie Bauer® brands, is pleased to announce major developments in its Vyrb social audio app, which is in open beta on iOS and Android.
Vyrb is a full social media platform designed for wearables, which offers a suite of tools for creating, sharing and enjoying audio content in a frictionless, handsfree format. Whilst it offers a complete visual interface, the app provides a set of unique handsfree social utilities accessed through voice assistants like Siri®. The company has just completed a powerful new live broadcasting feature called “On Air”, which enables users to create real-time audio chatrooms with up to 100 visitors and multiple active speakers. The company believes this feature will be a useful tool for audio content creators and collaborative work.
“Lucyd Eyewear is not simply another smartglass, it is an evolution in optical eyewear that makes it easier than ever to create and consume audio content,” says Innovative Eyewear CEO Harrison Gross. “We are supporting our hardware platform with audio-focused software to enable seamless communication, content generation and social interaction on our frames as well as other wearables. The introduction of the On Air feature to our Vyrb app is a milestone where we have enhanced the popular and useful real-time chat functionality found in other social apps, by adapting it to an ecosystem purpose-built for wearable communications. Now, Vyrb users will be able to communicate with an expansive team and host live audio events with large audiences. After a user concludes an On Air session, they have the option to save a recording of it on their Vyrb profile and share to other platforms.“
In addition to the On Air feature, Vyrb’s latest release includes an audio upload feature that allows users to port audio files they created outside of Vyrb into the app, mix in sound effects, and share to their profile. This feature enables content creators to quickly upload their audio content library into Vyrb.
Download Vyrb™ on iOS/Mac and Android to explore the beta app. Watch a video of Vyrb in action here.
About Innovative Eyewear, Inc.
Innovative Eyewear is a developer and retailer of cutting-edge smart eyewear, under the Lucyd®, Nautica® & Eddie Bauer® brands. True to our mission to Upgrade Your Eyewear®, our Bluetooth audio glasses allow users to stay safely and ergonomically connected to their digital lives, and are offered in hundreds of frame and lens combinations to meet the needs of the optical market. To learn more and explore our continuously evolving collection of smart eyewear, please visit www.lucyd.co.
Tekcapital currently owns 5,189,086 shares (approximately 71%) of Innovative Eyewear, Inc.
For further information, please contact:
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Tekcapital Plc |
Via Flagstaff |
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Clifford M. Gross, Ph.D. |
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SP Angel Corporate Finance LLP (Nominated Adviser and Broker) |
+44 (0) 20 3470 0470 |
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Richard Morrison/Charlie Bouverat (Corporate Finance)/Abigail Wayne / Rob Rees (Corporate Broking)
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Flagstaff Strategic and Investor Communications |
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+44 (0) 20 7129 1474 |
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Tim Thompson/Andrea Seymour/Fergus Mellon |
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About Tekcapital plc
Tekcapital creates value from investing in new, university-developed discoveries that can enhance people’s lives and provides a range of technology transfer services to help organisations evaluate and commercialise new technologies. Tekcapital is quoted on the AIM market of the London Stock Exchange (AIM: symbol TEK) and is headquartered in the UK. For more information, please visit www.tekcapital.com.
LEI: 213800GOJTOV19FIFZ85
Forward-Looking Statements
This press release is for informational purposes only. The information herein does not constitute investment advice nor an offer to invest and may contain statements related to our future business and financial performance and future events or developments involving Innovative Eyewear, Inc., Lucyd or Tekcapital that may constitute forward-looking statements. These statements may be identified by words such as “expect,” “look forward to,” “anticipate” “intend,” “plan,” “believe,” “seek,” “estimate,” “will,” “project” or words of similar meaning. We may also make forward-looking statements in other reports, in presentations, in material delivered to customers, stakeholders and in press releases. In addition, our representatives may from time to time make oral forward-looking statements. Such statements may be based on the current expectations and certain assumptions of Tekcapital, Innovative Eyewear Inc. or Lucyd’s management. Please note that these are subject to a number of risks, uncertainties and factors, including, but not limited to those described in various disclosures. Should one or more of these risks or uncertainties materialize, or should underlying expectations not occur or assumptions prove incorrect, actual results, performance or achievements of Innovative Eyewear Inc., Lucyd and/or Tekcapital may vary materially from those described explicitly or implicitly in the relevant forward-looking statement. Other than as required by relevant regulation or law, neither Innovative Eyewear Inc, Lucyd nor Tekcapital intends, nor assumes any obligation, to update or revise these forward-looking statements in light of developments which differ from those anticipated.